In a large mixing bowl, combine ground chicken, finely chopped chipotle pepper, adobo sauce, smoked paprika, ground cumin, garlic powder, onion powder, and a sprinkle of salt and black pepper. Squeeze in lime juice, add breadcrumbs and egg, then mix thoroughly.

Divide the mixture into four equal portions, shaping each into a patty about 1/2 inch thick, creating a slight indentation in the center.

Preheat grill or skillet over medium heat. Lightly oil the surface and cook patties for 6-7 minutes on each side, until golden brown and reaching an internal temperature of 165°F. Optionally add pepper jack cheese during the last minute.

Prepare the chipotle mayo by whisking together mayonnaise, chopped chipotle pepper, lime juice, and garlic powder. Adjust seasoning with salt to taste.

Toast burger buns until golden brown. Spread chipotle mayo on the bottom half, layer with lettuce, chicken patty, sliced tomato, and red onion. Add pickled jalapeños if desired, then cap with the top bun.

Serve immediately with sides like fries or coleslaw, enjoying the balance of smokiness and freshness.